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Faculty Member Details

Staff Id : 04461
Name : Dr. S. MANOHARAN
Designation : PROFESSOR & HEAD
Department : BIOCHEMISTRY & BIOTECHNOLOGY
Qualification : M.Sc.,M.Phil.,Ph.D.,
Specialization : CANCER BIOLOGY, DIABETES MELLITUS
Date of Birth : 21-02-1969
Date of Joining : 16-02-2000
Present Address Contact Number E-Mail Address
41,Thillai Nagar,
Chidambaram - 608 001.
9442548117sakshiman@rediffmail.com
Research Guidance
Discipline Awarded Guidance
M.Phil./M.E./M.Sc. 70-
Ph.D. 204


Conference /Seminar / Symposia / Workshop
Conference Seminar Symposia Workshop
National International
Attended 84333
Conducted 82--1


Research Projects
Major Projects Minor Projects Total Amount (Rs.)
Completed 5-77,08,610
Ongoing 1-10,00,000
Teaching and Research Experience Industry Experience
24 Years -
Journals Conference Books Published Popular Article
National International National International
36 145 6 - 3 -

List of Publications - National
K. Vasudevan , T.Satesh , S. Manoharan, "Stimulatory Influence of select Spices on Gastric Acid Secretion in Anaesthetized Wistar Rats.", Journal of medical science and clinical research 8 (9), 271-276,2020, Volume 8, Number 9, Sep 2020, pp. 271-276. 2020.
Manoj Prabhakar, M.; Manoharan, S.; Ignacimuthu, S.; Stalin, A. , "In silico docking analysis to explore the pro-apoptotic and anti-cell proliferative potential of ferulic acid.", Indian. J. Biochem. Biophys., Volume 53, Number 1&2, 2016, pp. 17-23. 2016.
Manimaran, A.; Manoharan, S.;Selvasundaram, R.; Buddhan, R.; Neelakandan M , "Protective efficacy of Emodin on the expression of inflammatory and angiogenic markers in experimental oral carcinogenesis...", J. Chem. Pharm. Res. , Volume 8, Number 8, 2016, pp. 507-513. 2016.
Palanimuthu, D., Manoharan, S., Baskaran, N., Rajasekaran, D., Srinivasan, R. and Shamsul Afaq Wani. , "Anti-clastogenic potential of lupeol against 7,12-dimethylbenz(a)anthracene induced clastogenesis.", Journal of Cell and Tissue Research, Volume 12, Number 1, 2012, pp. 2999-3002. 2012.
Sharmila R and Manoharan S., "Evaluation of anti-tumor initiating and anti-tumor promoting effects of rosmarinic acid in 7,12-dimethylbenz(a)anthracene (DMBA) induced skin carcinogenesis in Swiss albino mice.", Indian J Exp Biol, Volume 50, Number 3, 2012, pp. 187-194. 2012.
Vasanthaselvan M and Manoharan S. , "Chemopreventive potential of geraniol in 7,12-dimethylbenz[a]anthracene (DMBA) induced skin carcinogenesis in Swiss albino mice.", J. Environ Biol, Volume 33, Number 1, 2012, pp. 255-260. 2012.
Srinivasan, R and Manoharan S, "Chemopreventive potential of chrysin in 7,12-dimethylbenz(a)anthracene induced mammary carcinogenesis in sprague-dawley rats.", Journal of Cell and Tissue Research, Volume 11, Number 3, 2011, pp. 2909-2918. 2011.
Kowsalya R, Manoharan S, Silvan S, Baskaran N and Palanimuthu D. , "Antigenotoxic potential of 18-Glycrrhrtinic acid in 7,12-dimethylbenz(a)anthracene (DMBA) induced genotoxicity in golden Syrian hamsters.", Journal of Cell and Tissue Research, Volume 11, Number 2, 2011, pp. 1-8. 2011.
Vinothkumar V, Manoharan S, Palanimuthu D, Rajasekaran D, Srinivasan R and Shamsul Afaq Wani, "Geraniol protects cell surface glycoconjugates abnormalities during 7, 12-dimethylbenz[a]nthraceneinduced oral carcinogenesis.", Journal of Cell and Tissue Research, Volume 11, Number 2, 2011, pp. 2759-2764. 2011.
Manoharan S, Singh A.K, Silvan S, Baskaran N, Karthikeyan S and Manoj Prabhakar M, "Antigenotoxic efficacy of andrographolide in 7,12-dimethylbenz[a]anthracene-induced genotoxicity in bone marrow cells of hamsters.", Journal of Cell and Tissue Research, Volume 11, Number 2, 2011, pp. 2751-2758. 2011.
Manoharan, S. and Pugalendhi, P, "Breast cancer : An overview .", Journal of Cell and Tissue Research, Volume 10, Number 3, 2010, pp. 2423-2432. 2010.
Sindhu, G. and Manoharan, S, "Berberine protects cellular integrity during 7, 12- dimethylbenz[a] anthracene-induced oral carcinogenesis in golden syrian hamsters .", Journal of Cell and Tissue Research. , Volume 10, Number 2, 2010, pp. 2185-2190. 2010.
Manoj prabhakar, R. Madavan Nirmal, S. Silvan, N. Baskaran, M. Muneeswaran and S. Manoharan, "Protective effect of berberine on immunoexpression pattern of p53 and bcl-2 in 7,12-dimethylbenz[a]anthracene-induced skin carcinogenesis in swiss albino mice.", Journal of Cell and Tissue Research , Volume 10, Number 2, 2010, pp. 2293-2297. 2010.
Pugalendhi P, Manoharan S, Sindhu G, Vinothkumar V, Baskaran N., "Protective effect of genistein and daidzein, in combination, against 7,12-dimethylbenz(a)anthracene induced chromosomal aberrations and DNA damage in bone marrow cells of female Sprague-Dawley rats.", Journal of Cell and Tissue Research, Volume 10, Number 3, 2010, pp. 2305-2309. 2010.
Subramanian Balakrishnan, Shanmugam Manoharan, Linsa Mary Alias and Madavan R Nirmal , "Effect of curcumin and ferulic acid on modulation of expression pattern of p53 and bcl-2 proteins in 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.", Indian J Biochem Biophys, Volume 47, Number 1, 2010, pp. 7-12. 2010.
Balakrishnan S, Manoharan S, Linsa Mary A, Vellaichamy L, Menon VP, Nirmal MR., "Modulating effects of curcumin and ferrulic acid on expression pattern of p53 and bcl-2 proteins in 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.", Indian J Biochem Biophys, Volume 47, Number 1, 2010, pp. 7-12. 2010.
Baskaran, K., Satish, R., Santhosh, V., Santha, K., Manoharan, S.,Inmozhi, R. and Sethupathy, S. , "Status of sialic acid in patients with cervical intraepithelial neoplasia and cervical carcinoma .", Journal of Cell and Tissue Research, Volume 10, Number 3, 2010, pp. 2375-2378. 2010.
Shanmugam Manoharan, Malairajan Gitanjali, Linsa Mary Alias, Alagappan Chellammal, Kalaiarasan Vasudevan, Subramanian Balakrishnan and Lakshmanan Vellaichamy, "Antihyperglycemic and Antilipidperoxdative Potential of Ceiba Pentandra in Streptozotocin-Induced Diabetic Rats.", J Cell Tissue Res, Volume 9, Number 1, 2009, pp. 1731-1736. 2009.
Boopathy Raja, A., Elanchezhiyan, C., Manoharan, S., Suresh, K., Balakrishnan, S. and Sethupathy, S , "Evaluation of antihyperglycemic potential of Helicteres isora in streptozotocin induced diabetic Wistar rats..", J Cell Tissue Res, Volume 9, Number 2, 2009, pp. 1925-1928. 2009.
Manoharan, S., Kolanjiappan, K., Suresh, K., Vasudevan, K., Balakrishnan, S. and Pugalendhi, P , "Protective effect of Jasminum grandiflorum flower extract on cell surface abnormalities during DMBA-induced mammary carcinogenesis.", J Cell Tissue Res, Volume 9, Number 2, 2009, pp. 1811-1815. 2009.
Vasudevan, K, Manoharan, S, Linsamary, A, Balakrishnan, S, Pugalendhi, P, Baskaran, N, Silvan, S , "Antidiabetic and antilipid peroxidative effects of Cassia fistula (Linn.) flowers in streptozotocin induced diabetic rats.", J Cell Tissue Res, Volume 9, Number 1, 2009, pp. 1745-1749. 2009.
Blessy D, Suresh K, Manoharan S, Arokia Vijayanand M and Sugunadevi G , "Evaluation of chemopreventive potential of Zingiber officinale roscoe ethanolic root extract on DMBA induced oral carcinogenesis.", Research Journal of Agriculture and Biological Sciences, Volume 5, Number 1, 2009, pp. 775-778. 2009.
Manoharan, S., Mohan, R., Balakrishnan, S., Vellaichamy, L., Vasudevan, K., Linsa Mary, A., Baskaran, N, "Modifying effects of metformin on circadian pattern of blood glucose, lipid peroxidation and enzymatic antioxidants in alloxan induced diabetic rats..", E J Pharmacol Ther, Volume 2, Number 1, 2009, pp. 19-23. 2009.
Manoharan, S., Chellammal, A., Linsa Mary, A., Vasudevan, K., Balakrishnan, S., Ranezab Anishkumar, P, "Antidiabetic efficacy of Tamarindus indica seeds in alloxan induced diabetic rats.", E J Pharmacol Ther, Volume 2, Number 1, 2009, pp. 13-18. 2009.
Suresh K, Manoharan S, Blessy D, "Antigenotoxic effect of Annona squamosa leaf extract in DMBA induced genotoxicity.", KUMJ, Volume 6, Number 1, 2009, pp. 44-49. 2009.
S. Manoharan, K. Panjamurthy, Venugopal P. Menon, S. Balakrishnan & Linsa Mary Alias, "Protective effect of Withaferin-A on tumour formation in 7,12-dimethylbenz[a]anthracene induced oral carcinogenesis i.", Indian J Exp Biol, Volume 47, Number 1, 2009, pp. 16-23. 2009.
Panjamurthy, K., Balakrishnan, S., Vellaichamy, L., Manoharan, S. and Linsa Mary, A. , "Withaferin-a protects biochemical changes in the buccal mucosa of Golden Syrian hamsters during 7,12-dimethylbenz [a] anthracene (DMBA) - induced oral carcinogenesis.", Journal of Cell and Tissue Research, Volume 8, Number 3, 2008, pp. 1505-1510. 2008.
Balakrishnan S, Manoharan S, Linsa Mary A, Vellaichamy L, Menon VP, "Protective effects of curcumin and ferulic acid on circadian pattern of lipid peroxidation and antioxidants in 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis.", J Cell Tissue Res, Volume 8, Number 6, 2008, pp. 1525-1530. 2008.
Manoharan S, Silvan S, Vasudevan K and Balakrishnan S, "Antihyperglycemic and antilipidperoxidative effects of Piper longum (Linn.) dried fruits in alloxan induced diabetic rats.", J Bio Sciences, Volume 6, Number 1, 2007, pp. 161-168. 2007.
Pavana P, Sethupathy S and Manoharan S, "Antihyperglycemic and antilipidperoxidative effects of tephrosia purpurea seed extract in streptozotocin induced diabetic rats .", Ind J Clin Biochem, Volume 22, Number 1, 2007, pp. 77-83. 2007.
Manoharan S, Panjamurthy K, Vasudevan K, Sasikumar D and Kolanjiappan K, "Protective Effect of Jasminum grandiflorum Linn. On DMBA-induced Chromosomal Aberrations in Bone Marrow of Wistar Rats.", Int J Pharmacol, Volume 2, Number 4, 2006, pp. 406-410. 2006.
Kavitha K, Manoharan S. , "Anticarcinogenic and antilipidperoxidative effects of Tephrosia purpurea (Linn.) Pers. in 7, 12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinoma.", Ind J Pharmacol, Volume 38, Number 2, 2006, pp. 185-189. 2006.
Punitha R, Vasudevan K, Manoharan S , "Effects of Pongamia pinnata flowers on blood glucose and oxidative stress in alloxan induced diabetic rats.", Ind J Pharmacol, Volume 38, Number 3, 2006, pp. 62-63. 2006.
Vijayakumar D, Suresh K and Manoharan S, "Altered lipids and lipoproteins pattern in erythrocyte membranes of rheumatoid arthritis patients.", Indian J Clin Biochem, Volume 20, Number 1, 2005, pp. 52-55. 2005.
Manoharn S, Kolanjiappan K. Suresh K and Panjamurthy K , "Lipid peroxidation and antioxidant status in patients with oral squamous cell carcinoma.", Ind J Med Res, Volume 122, Number 2, 2005, pp. 529-534. 2005.
Manoharan, S., Kavitha, K. and Nagini, S., "Role of life style on plasma and erythrocyte membrane lipid profile in gastric cancer patients.", Ind. J. Physiol. Pharmacol, Volume 41, Number 1, 1997, pp. 62-66. 1997.
List of Publications - International
RAJAMANICKAM BUDDHAN, SHANMUGAM MANOHARAN, RADHAKRISHNAN MURALI NAIDU, MOHAN KARTHIK, MANI NEELAKANDAN, "Chemopreventive Potential of Myrtenal in 7,12-Dimethylbenz(a) Anthracene Induced Experimental Oral Carcinogenesis in Golden Syrian Hamsters.", Journal of Clinical & Diagnostic Research, Volume 14, Number 4, 2020, pp. 1-6. 2020.
R. SHARMILA , K. GHOSH , S. MANOHARAN, "Rewiring of chemically modified MAPK pathway and its downstream targets by rosmarinic acid in mice dermal cancer.", Journal of Information and Computational Science, Volume 10, Number 1, 2020, pp. 1047-1064. 2020.
Buddhan R, ,Manoharan S, Muralinaidu R, "Myrtenalavertsapoptoticevasionofcancercellsin7,12-dimethylbenz(a)anthraceneinducedexperimentaloralcarcinogenesis.", Int.J.Res.Pharm.Sci, Volume 11, Number 3, 2020, pp. 2838-2847. 2020.
Renganathan Selvasundaram, Shanmugam Manoharan, Rajamanickam Buddhan, Mani Neelakandan and Radhakrishnan Murali Naidu. , "Chemopreventive potential of Esculetin in 7,12-dimethylbenz(a) anthracene induced hamster buccal pouch carcinogenesis. .", Mol. Cellular Biochem., Volume 448, Number 1-2, 2018, pp. 145-153. 2018.
Manimaran, A.; Manoharan, S. , "Tumor preventive efficacy of emodin in 7,12-dimethylbenz[a] anthracene-induced oral carcinogenesis: a histopathological and biochemical approach. .", Pathol. Oncol. Res. , Volume 24, Number 1, 2018, pp. 19-29. 2018.
7. Buddhan, R.; Manoharan, S, "Diosmin reduces cell viability of A431 skin cancer cells through apoptotic induction..", J. Can. Res. Therap, Volume 13, Number 3, 2017, pp. 471-476. 2017.
Manimaran, A.; Buddhan, R.; Manoharan, S, ". Emodin downregulates cell proliferation markers during DMBA induced oral carcinogenesis in golden Syrian hamsters. . .", African Journal of Traditional, Complementary and Alternative Medicines, Volume 14, Number 2, 2017, pp. 83-91. 2017.
Pavana Pamu, Manoharan Shanmugam, Sethupathy Subramanian, "Beneficial effects of Tephrosia purpurea ethanolic seed extract on lipids and membrane bound enzymes in experimental diabetic rats.", J Young Pharm, Volume 9, Number 4, 2017, pp. 550-554. 2017.
12. Velvizhi V, Manoharan S, Shabana Begum M, Manimaran A and Buddhan R. , "Cissus quadrangularis inhibits tumor formation during 7, 12-dimethylbenz (a) anthracene induced oral carcinogenesis..", Int J Recent Sci Res, Volume 8, Number 12, 2017, pp. 22582-22586. 2017.
11. Hemalatha, K, Manoharan, S, Shabana Begum, M, Manoj Prabhakar, M and Neelakandan, M. , "Protective efficacy of cajanus cajan on plasma and buccal mucosa glycoconjugates in DMBA induced hamster buccal pouch carcinogenesis.", Int J Recent Sci Res, Volume 8, Number 12, 2017, pp. 22587-22590. 2017.
Velu Velvizhi, Shanmugam Manoharan, Musthafa Shabana Begum, Rajamanickam Buddhan. , "Cissus quadrangularis protects cell surface glycoconjugates during 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis..", International Journal of Research in Pharmaceutical Sciences, Volume 8, Number 4, 2017, pp. 493-498. 2017.
Kuselar Hemalatha, Shanmugam Manoharan, Musthafa Shabana Begum, Mani Neelakandan. , "Tumor suppressing potential of Cajanus cajan in 7,12-dimethylbenz(a) anthracene (DMBA)-induced hamster buccal pouch carcinogenesis..", International Journal of Research in Pharmaceutical Sciences, Volume 8, Number 4, 2017, pp. 504-511. 2017.
Kowsalya R and Manoharan S, "Health status of the Indian women – A Brief report .", MOJ Proteomics Bioinform, Volume 5, Number 3, 2017, pp. 109-111. 2017.
Manoharan, S.; Karthikeyan, S.; Manimaran, "Anti-inflammatory and anti angiogenic potential of cromolyn in 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.", Int. J. Pharm. Pharm. Sci, Volume 8, Number 1, 2016, pp. 321-324. 2016.
. Manoharan, S.; Karthikeyan, S.; Essa, M. M.; Manimaran, A.; Selvasundaram R, "An overview of oral carcinogenesis.", Int. J. Nutr. Pharmacol. Neurol. Dis. , Volume 6, Number 2, 2016, pp. 51-62. 2016.
Manimaran, A.; Manoharan, S.; Neelakandan M , "Emodin efficacy on the Akt, MAPK, ERK and DNMT expression pattern during DMBA induced oral carcinoma in golden Syrian hamsters.", African Journal of Traditional, Complementary and Alternative Medicines, Volume 13, Number 6, 2016, pp. 186-193. 2016.
5. Manoharan, S.; Mohammed Essa, M.; Vinoth, A.; Kowsalya, R.; Manimaran, A, Selvasundaram, R, "Alzheimer’s diseases and medicinal plants: An overview.", Adv. Neurobio, Volume 12, Number ---, 2016, pp. 95-105. 2016.
Manoharan, S.; Guillemin, G. J.; Essa, M. M.; Abiramasundari, R. S.; Akbar M, Akbar, M. D, "The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review.", Oxid Med Cell Longev, Volume 2016, Number --, 2016, pp. 1-15. 2016.
SEKAR KARTHIKEYAN AND SHANMUGAM MANOHARAN, "CROMOLYN INHIBITS 7, 12-DIMETHYLBENZ (A) ANTHRACENE INDUCED ORAL CANCER THROUGH APOPTOTIC INDUCTION AND SUPPRESSION OF CELL PROLIFERATION.", Int J Pharm Bio Sci , Volume 7, Number 1, 2016, pp. 35-42. 2016.
SEKAR KARTHIKEYAN AND SHANMUGAM MANOHARAN, "TUMOR PREVENTIVE POTENTIAL OF CROMOLYN IN 7, 12-DIMETHYLBENZ(A)ANTHRACENE INDUCED HAMSTER BUCCAL POUCH CARCINOGENESIS.", Int J Pharm Bio Sci, Volume 7, Number 1, 2016, pp. 24-34. 2016.
Manoharan, S.; Manoj Prabhakar, M, "Chemopreventive efficacy of Adhatoda vasica leaves in 7,12-dimethylbenz[a]anthracene induced oral carcinogenesis.", International Journal of Pharma and Bio Sciences , Volume 6, Number 1, 2015, pp. 731-741. 2015.
Manoharan, S.; Karthikeyan, S.; Kowsalya, R.; Manimaran, A.; Vasudevan, K., "155. Modulating effect of cromolyn on Akt, ERK and DNMT expression pattern in 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis. .", Int. J. Res. Pharm. Sci, Volume 6, Number 4, 2015, pp. 299-304. 2015.
Shanmugam Manoharan , Duraisamy Rajasekaran , Murugaraj Manoj Prabhakar Sekar Karthikeyan , Asokan Manimaran , "Modulating Effect of Enicostemma Littorale on the Expression Pattern of Apoptotic, Cell Proliferative, Inflammatory and Angiogenic Markers During 7, 12-Dimethylbenz (A) Anthracene Induced Hamster Buccal Pouch Carcinogenesis.", Toxicol Int ., Volume 22, Number 1, 2015, pp. 130-140. 2015.
D Rajasekaran , S Manoharan , M M Prabhakar , A Manimaran , "Enicostemma Littorale Prevents Tumor Formation in 7,12-dimethylbenz(a)anthracene-induced Hamster Buccal Pouch Carcinogenesis.", Hum Exp Toxicol, Volume 34, Number 9, 2015, pp. 911-921. 2015.
Manimaran, A.; Manoharan, S.; Karthikeyan, S.; Nirmal, M. R. , "143. Anti-cell proliferative, anti-inflammatory and anti-angiogenic potential of lupeol in 7,12-dimethylbenz(a) anthracene induced hamster buccal pouch carcinogenesis..", Br. J. Med. Med. Res, Volume 6, Number 6, 2015, pp. 587-596. 2015.
N Krishnakumar, NK Sulfikkarali, S Manoharan, P Venkatachalam, "Raman spectroscopic investigation of the chemopreventive response of naringenin and its nanoparticles in DMBA-induced oral carcinogenesis.", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Volume 115, Number 2, 2014, pp. 648-653. 2014.
Rajasekaran D, Kowsalya R, Selvasundaram R, Manoharan S, "Enicostemma littorale protects cell surface abnormalities during DMBA-induced hamster buccal pouch carcinogenesis.", Int J Pharm Bio Sci, Volume 6, Number 1, 2014, pp. 104-109. 2015.
Prabhakar MM, Manoharan S, Rejitharaji T, Selvasundaram R, Hairul Islam VI, "Ferulic acid reduces cell viability through its apoptotic efficacy: An in vitro approach.", Br J Med Med Res, Volume 5, Number 5, 2014, pp. 612-621. 2015.
Manoharan S, Rejitharaji T, Prabhakar MM, Karthikeyan S, Hairul Islam VI, "Apigenin reduces cell viability of Human epidermoid cancer cells (Hep-2). .", Int J Res Pharm Sci. , Volume 5, Number 3, 2014, pp. 152-158. 2014.
Manoharan S, Rejitharaji T, Prabhakar MM, Manimaran A, Singh RB, "Modulating Effect of Ferulic Acid on NF-κB, COX-2 and VEGF Expression Pattern During 7, 12- Dimethylbenz(a)anthracene Induced Oral Carcinogenesis.", Open Nutraceuticals J, Volume 7, Number 1, 2014, pp. 33-38. 2014.
Manoharan S, Prabhakar MM, "Adhatoda vasica Leaves Protect Cell Surface Glycoconjugates Abnormalities During DMBA Induced Hamster Buccal Pouch Carcinogenesis..", International Journal of Pharmacognosy and Phytochemical Research, Volume 6, Number 4, 2014, pp. 817-821. 2014-2015.
Karthikeyan S, Manoharan S, "Chemopreventive potential of chrysin in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis.", Int J Nutr Pharmacol Neurol Diseases, Volume 3, Number 1, 2013, pp. 46-53. 2013.
Duraisamy Rajasekaran, Shanmugam Manoharan, Simon Silvan, Krishnamoorthy Vasudevan, Nagarethinam Baskaran and Duraisamy Palanimuthu, "Proapoptotic, anti-cell proliferative, anti-inflammatory and anti-angiogenic potential of carnosic acid during 7,12 dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. .", African J Trad Comp Med, Volume 10, Number 1, 2013, pp. 102-112. 2013.
S Manoharan, SA Wani, K Vasudevan, A Manimaran, MM Prabhakar, "Saffron Reduction of 7, 12-Dimethylbenz [a] anthracene-induced Hamster Buccal Pouch Carcinogenesis..", Asian Pacific Journal of Cancer Prevention, Volume 14, Number 2, 2013, pp. 951-957. 2013.
N Sulfikkarali, N Krishnakumar, S Manoharan, RM Nirmal. , "Chemopreventive efficacy of naringenin-loaded nanoparticles in 7, 12-dimethylbenz (a) anthracene induced experimental oral carcinogenesis.", Pathology & Oncology Research, Volume 19, Number 2, 2013, pp. 287-296. 2013.
Manoharan S, Sindhu G, Vinothkumar V and Kowsalya R, "Berberine prevents 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis: A biochemical approach.", Eur J Cancer Prev, Volume 2, Number 1, 2012, pp. 182-192. 2012.
Manoharan S, Kowsalya R, Baskaran N, Silvan S, Sindhu G, Vinothkumar V, "Protective effect of 18-Glycrrhrtinic acid in cell surface glycoconjugates abnormalities in 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis.", Int J Nutr Pharmacol Neurol Diseases , Volume 2, Number 2, 2012, pp. 151-155. 2012.
Sundaraganesan N, Mariappan G, Manoharan S., "Molecular structure and vibrational spectroscopic studies of Chrysin using HF and Density Functional Theory.", Spectrochim Acta A Mol Biomol Spectrosc, Volume 87, Number 4, 2012, pp. 67-76. 2012.
Palanimuthu D and Manoharan S, "Lupeol protects abnormalities in cell surface moities during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.", International Journal of Pharmaceutical Sciences and Research, Volume 3, Number 5, 2012, pp. 1337-1342. 2012.
Mariappan G, Sundaraganesan N, Manoharan S, "The spectroscopic properties of anticancer drug Apigenin investigated by using DFT calculations, FT-IR, FT-Raman and NMR analysis..", Spectrochim Acta A Mol Biomol Spectrosc, Volume 95, Number 1, 2012, pp. 86-99. 2012.
Manoharan Shanmugam, Arjun Kumar Singh, Baskaran Nagarethinam, Karthikeyan Sekar., "Pro-apoptotic and anti-inflammatory potential of andrographolide during 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis. .", J Exp Integr Med, Volume 2, Number 1, 2012, pp. 313-319. 2012.
Arjun Kumar Singh, Manoharan Shanmugam, Kathiresan Suresh, Duraisamy Rajasekaran., "Modulating effect of Andrographolide on cell surface glycoconjugates status during 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis. .", Int J Res Pharm Sci , Volume 3, Number 2, 2012, pp. 200-205. 2012.
Mariappan G, Sundaraganesan N, Manoharan S, "Experimental and theoretical spectroscopic studies of anticancer drug rosmarinic acid using HF and density functional theory..", Spectrochim Acta A Mol Biomol Spectrosc, Volume 97, Number 1, 2012, pp. 340-351. 2012.
Silvan S, Manoharan S, "Apigenin prevents deregulation in the expression pattern of cell-proliferative, apoptotic, inflammatory and angiogenic markers during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis..", Arch Oral Biol, Volume 58, Number 1, 2012, pp. 94-101. 2013.
Vinothkumar V, Manoharan S, Sindhu G, Nirmal MR, Vetrichelvi V, "Geraniol modulates cell proliferation, apoptosis, inflammation, and angiogenesis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis..", Mol Cell Biochem, Volume 369, Number 1-2, 2012, pp. 17-25. 2012.
Vinothkumar V, Manoharan S, Sindhu G, Nirmal MR, Vetrichelvi V, "Geraniol modulates cell proliferation, apoptosis, inflammation, and angiogenesis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis..", Mol Cell Biochem, Volume 369, Number 1-2, 2012, pp. 17-25. 2012.
Vinothkumar V, Manoharan S, Sindhu G, Nirmal MR, Vetrichelvi V, "Geraniol modulates cell proliferation, apoptosis, inflammation, and angiogenesis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis..", Mol Cell Biochem, Volume 369, Number 1-2, 2012, pp. 17-25. 2012.
Palanimuthu D, Baskaran N, Silvan S, Rajasekaran D, Manoharan S, "Lupeol, A Bioactive Triterpene, Prevents Tumor Formation During 7,12-Dimethylbenz(a)anthracene Induced Oral Carcinogenesis..", Pathol Oncol Res, Volume 18, Number 4, 2012, pp. 1029-1037. 2012.
Baskaran N, Manoharan S, Kowsalya R, Silvan N, Palanimuthu D., "Coumarin modulates apoptotic, cell proliferative, inflammatory and angiogenic markers in favor of tunor inhibition during 7,12 dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.", Int J Res Pharm Sci , Volume 3, Number 1, 2012, pp. 1-19. 2012.
Manoharan S, Arjun Kumar Singh K, Suresh K, Vasudevan R, Subhasini and Baskaran N, "Anti-tumor initiating potential of andrographolide in 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis.", Asian Pacific J Can Prev, Volume 13, Number 6, 2012, pp. 5701-5708. 2012.
Manoharan S, Palanimuthu D, Baskaran N, Silvan S. , "Modulating effect of Lupeol on the Expression pattern of Apoptotic markers in 7,12-dimethylbenz[a]anthracene induced Oral carcinogenesis.", Asian Pacific J Can Pre , Volume 13, Number 11, 2012, pp. 1-4. 2012.
Manoj prabhakar M and Manoharan S, "Anti – cell proliferative efficacy of Ferulic acid against 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis.", Asian Pacific J Can Prev, Volume 13, Number 10, 2012, pp. 5207-5211. 2012.
Baskaran N, Manoharan S, Karthikeyan S, Prabhakar MM, "Chemopreventive potential of Coumarin in 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis.", Asian Pacific J Can Prev, Volume 13, Number 10, 2012, pp. 5273-5279. 2012.
Pachaiappan Pugalendhi, Shanmugam Manoharan, Kathiresan Suresh, Nagarethinam Baskaran., "Genistein and daidzein, in combination, protect cellular integrity during 7,12-dimaethylbenz(a)anthracene (DMBA) induced mammary carcinogenesis in Sprague-Dawley rats.", Afr J Tradit Complement Altern Med, Volume 8, Number 2, 2011, pp. 91-97. 2011.
Manoharan S, Umadevi S, Jayanthi S and Baskaran N. , "Antihyperglycemic effect of Coscinium fenestratum and Catharanthus roseus in alloxan-induced diabetic rats.", Int J Nutr Pharmacol Neurol Diseases , Volume 1, Number 1, 2011, pp. 189-193. 2011.
Manoharan S, Vasantha Selvan M, Silvan S, Muralinaidu R and Baskaran N. , "Carnosic acid protects cell surface glycoconjugates abnormalities during 7,12-dimethylbenz(a)anthracene(DMBA) induced oral carcinogenesis.", Int J Res Pharm Sci, Volume 2, Number 1, 2011, pp. 1-7. 2011.
Vinothkumar V, Manoharan S, Sindhu G and Kowsalya R. , "Chemopreventive efficacy of geraniol against 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.", Redox report, Volume 16, Number 1, 2011, pp. 91-100. 2011.
Manoharan S, "International Congress on Nutrition in Cardiovascular Diseases .", International Journal of Nutrition, Pharmacology, Neurological Diseases, Volume 1, Number 1, 2011, pp. 3-18. 2011.
Silvan S, Manoharan S, Baskaran N, Karthikeyan S and Manoj Prabhakar M. , "Protective effect of apigenin on 7, 12-dimethylbenz[a]anthracene-induced glycoconjugates in the plasma and buccal mucosa of golden Syrian hamsters. .", International Journal of Pharmaceutical Sciences and Research, Volume 2, Number 1, 2011, pp. 1753-1758. 2011.
Rajasekaran D, Manoharan S, Baskaran N and Vasudevan K, "Evaluation of chemopreventive efficacy of citral in 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis.", Int J Res Phytochem Pharmacol , Volume 1, Number 3, 2011, pp. 136-143. 2011.
Anusuya C and Manoharan S. , "Anti-tumor initiating potential of rosmarinic acid in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis.", J Environ Pathol Toxicol Oncol, Volume 30, Number 1, 2011, pp. 199-211. 2011.
Silvan S, Manoharan S, Baskaran N, Anusuya C, Karthikeyan S and Manoj Prabhakar M., "Chemopreventive potential of apigenin in 7,12-dimethylbenz(a)anthracene-induced experimental oral carcinogenesis.", European Journal of Pharmacology, Volume 670, Number 2-3, 2011, pp. 571-577. 2011.
Baskaran N, Rajasekaran D and Manoharan S, "Coumarin protects 7,12-dimethylbenz(a)anthracene-induced genotoxicity in the bone marrow cells of golden Syrian hamsters..", Int J Nutr Pharmacol Neurol Diseases , Volume 1, Number 1, 2011, pp. 167-173. 2011.
Baskaran N, Manoharan S, Silvan S, Palanimuthu D, Rajasekaran D, Manoj Prabhakar M, Karthikeyan S, Srinivasan R and Shamsul Afaq Wani. , "Protective effect of coumarin on cell surface glycoconjugates abnormalities during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis.", Int J Biol Med Res. , Volume 2, Number 3, 2011, pp. 643-647. 2011.
Manoharan S, Kowsalya R, Silvan S, Baskaran N, Anusuya C, "Anti-lipid peroxidative potential of 18-Glycrrhrtinic acid 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis.", Int J Res Pharm Sci, Volume 2, Number 1, 2011, pp. 1-15. 2011.
Kowsalya R, Vishwanathan P and Manoharan S. , "Chemopreventive potential of 18-Glycrrhrtinic acid, an active constituents of liquorice, in 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis.", Pak J Biol Sci, Volume 14, Number 11, 2011, pp. 619-624. 2011.
Shanmugam Manoharan, Ganapathy Sindhu, Madhavan Ramados Nirmal, Venkatesan Vetrichelvi and Subramanian Balakrishnan, "Protective effect of berberine on expression pattern of apoptotic, cell proliferative, inflammatory and angiogenic markers during 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis. .", Pak J Biol Sci, Volume 14, Number 20, 2011, pp. 2909-2918. 2011.
Shanmugam Manoharan, Ganapathy Sindhu, Madhavan Ramados Nirmal, Venkatesan Vetrichelvi and Subramanian Balakrishnan, "Protective effect of berberine on expression pattern of apoptotic, cell proliferative, inflammatory and angiogenic markers during 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis. .", Pak J Biol Sci, Volume 14, Number 20, 2011, pp. 2909-2918. 2011.
Shanmugam Manoharan, Ganapathy Sindhu, Madhavan Ramados Nirmal, Venkatesan Vetrichelvi and Subramanian Balakrishnan, "Protective effect of berberine on expression pattern of apoptotic, cell proliferative, inflammatory and angiogenic markers during 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis. .", Pak J Biol Sci, Volume 14, Number 20, 2011, pp. 2909-2918. 2011.
Pugalendhi P, Manoharan S, "Chemopreventive potential of genistein and daidzein in combination during 7,12-dimethylbenz(a)anthracene (DMBA) induced mammary carcinogenesis in Sprague-Dawley rats..", Pak J Biol Sci, Volume 13, Number 6, 2010, pp. 279-286. 2010.
Sindhu G, Manoharan S, "Anti-Clastogenic Effect of Berberine against DMBA-Induced Clastogenesis.", Basic Clin Pharmacol Toxicol, Volume 107, Number 4, 2010, pp. 818-824. 2010.
Baskaran N, Manoharan S, Balakrishnan S, Pugalendhi P., "Chemopreventive potential of ferulic acid in 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats.", Eur J Pharmacol, Volume 637, Number 1-3, 2010, pp. 22-29. 2010.
Suunadevi G, Suresh K, Manoharan S, Arokia Vijayanand M and Rajalingam K , "Modifying effects of Mosinone-A on glycoconjugates levels in DMBA induced hamster buccal pouch carcinogenesis.", Asian J Res Chem , Volume 3, Number 3, 2010, pp. 459-463. 2010.
Suresh K, Manoharan S, Arokia Vijayanand M and Sugunadevi G , "Chemopreventive and antioxidant efficacy of [6]-paradol in DMBA induced hamster buccal pouch carcinogenesis.", Pharmacol Rep, Volume 62, Number 6, 2010, pp. 1178-1185. 2010.
Suresh K, Manoharan S, Vijayaanand MA, Sugunadevi G., "Modifying Effects of Annona Squamosa Linn on Glycoconjugates Levels in 7, 12-Dimethylbenz (A) Anthracene (DMBA) Induced Hamster Buccal Pouch Carcinogenesis.", Journal of Applied Science Research, Volume 6, Number 5, 2010, pp. 973-974. 2010.
Suresh K, Manoharan S, Vijayaanand MA, Sugunadevi G., "Modifying Effects of Annona Squamosa Linn on Glycoconjugates Levels in 7, 12-Dimethylbenz (A) Anthracene (DMBA) Induced Hamster Buccal Pouch Carcinogenesis.", Journal of Applied Science Research, Volume 6, Number 5, 2010, pp. 973-974. 2010.
Shanmugam Manoharan, Subramanian Balakrishnan, Veerasamy Vinothkumar and Simon Silvan, "Anticlastogenic potential of carnosic acid against DMBA induced clastogenesis .", Pharmacol Rep, Volume 62, Number 6, 2010, pp. 1170-1177. 2010.
Pugalendhi P, Manoharan S. , "Chemopreventive potential of genistein and daidzein in combination during 7,12-dimethylbenz(a)anthracene (DMBA) induced mammary carcinogenesis in Sprague-Dawley rats.", Pak J Biol Sci , Volume 13, Number 2, 2010, pp. 279-286. 2010.
Pachaiappan Pugalendhi, Shanmugam Manoharan, Nagarethinam Baskaran, Madhavan R. Nirmal, "Effects of genistein and daidzein in combination, on the expression pattern of biomolecular markers (p53, PCNA, VEGF, iNOS, Bcl-2, and Bax) during 7,12-dimethylbenz(a)anthracene (DMBA) induced mammary carcinogenesis in Sprague-Dawley rats.", Int J of Biol Med Res, Volume 1, Number 4, 2010, pp. 264-271. 2010.
Pachaippan Pugalendhi, Shanmugam Manoharan, Nagarethinam Baskaran., "Effects of genistein and daidzein, in combination, on immunoexpression pattern of ER, PR and HER-2/neu during 7, 12-dimethylbenz (a) anthracene induced mammary carcinogenesis in rats.", Int. J. Res. Pharm. Sci. , Volume 1, Number 4, 2010, pp. 421-427. 2010.
Shanmugam Manoharan, Mookkan Muneeswaran, Nagarethinam Baskaran , "Chemopreventive efficacy of berberine in 7,12-dimethylbenz[a]anthracene (DMBA) induced skin carcinogenesis in Swiss albino mice.", Int. J. Res. Pharm. Sci, Volume 1, Number 4, 2010, pp. 521-529. 2010.
Manoharan S, Vasanthaselvan M, Silvan S, Baskaran N, Kumar Singh A, Vinoth Kumar V., "Carnosic acid: a potent chemopreventive agent against oral carcinogenesis..", Chem Biol Interact, Volume 188, Number 3, 2010, pp. 616-622. 2010.
Krishnan Baskaran, Ramanathan Satish, Viswan Santhosh, Radhika Govindaraju, Shanmugam Manoharan, Subramanian Sethupathy , "xpression pattern of pro- and anti-apoptotic proteins in patients with squamous cell carcinoma of the uterine cervix.", Int. J. Res. Pharm. Sci, Volume 1, Number 4, 2010, pp. 546-550. 2010.
Sasikumar S,Mathi S Suzan M,Salaman AT, Manoharan S, Prema S , "Terminala arjuna modulates circulatory antioxidants on DMBA induced hamster buccal pouch carcinogenesis.", Oman Medical Journal, Volume 25, Number 2, 2010, pp. 276-281. 2010.
Panjamurthy K, Manoharan S, Nirmal MR, Vellaichamy L. , "Protective role of Withaferin-A on immunoexpression of p53 and bcl-2 in 7,12-dimethylbenz(a)anthracene-induced experimental oral carcinogenesis.", Invest New Drugs, Volume 27, Number 3, 2009, pp. 447-452. 2009.
Alias LM, Manoharan S, Vellaichamy L, Balakrishnan S, Ramachandran CR. , "Protective effect of ferulic acid on 7,12-dimethylbenz[a]anthracene-induced skin carcinogenesis in Swiss albino mice.", Exp Toxicol Pathol, Volume 61, Number 3, 2009, pp. 205-214. 2009.
Shanmugam Manoharan, Subramanian Balakrishnan, Venugopal P. Menon, and Linsa Mary Alias , "Chemopreventive efficacy of curcumin and piperine during 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis..", Singapore Med J. , Volume 50, Number 2, 2009, pp. 139-146. 2009.
Kuppusamy Panjamurthy, Shanmugam Manoharan, Subramanian Balakrishnan, Kathiresan Suresh, Madhavan R. Nirmal, Namasivayam Senthil and Linsa Marry Alias., "Protective effect of Withaferin-A on micronucleus frequency and detoxication agents during experimental oral carcinogenesis.", Afr. J. Trad. CAM, Volume 6, Number 1, 2009, pp. 1-8. 2009.
Shanmugam Manoharan, Kuppusamy Panjamurthy, Pachaiappan Pugalendi, Subramanian Balakrishnan, Kasinathan Rajalingam, Lakshmanan Vellaichamy and Linsa Marry Alias , "Protective role of Withaferin-A on red blood cell integrity during 7,12-dimethylbenz[a]anthracene induced oral carcinogenesis.", Afr. J. Trad. CAM, Volume 6, Number 1, 2009, pp. 94-102. 2009.
Manoharan S, Ranezab Anishkumar P, Panjamurthy K, Vellaichamy L. and Linsa Mary A, "Modifying effect of Punica granatum flowers on lipids and lipids-metabolizing enzymes status in streptozotocin induced diabetic rats.", World Heart Journal, Volume 1, Number 1, 2009, pp. 325-332. 2009.
Pavana P, Sethupathy S, Santha K, Manoharan S. , "Effects of Tephrosia purpurea aqueous seed extract on blood glucose and antioxidant enzyme activities in streptozotocin induced diabetic rats.", Afr. J. Trad. CAM , Volume 6, Number 1, 2009, pp. 78-86. 2009.
Pachaiappan Pugalendhi, Shanmugam Manoharan, Kuppusamy Panjamurthy, Subramanian Balakrishnan, Madhavan R. Nirmal, "Antigenotoxic effect of genistein against 7,12-dimethylbenz[a]anthracene induced genotoxicity in bone marrow cells of female Wistar rats. .", Pharmacol Rep, Volume 61, Number 2, 2009, pp. 296-303. 2009.
Vellaichamy L, Balakrishnan S, Panjamurthy K, Manoharan S, Linsa Mary A, "Chemopreventive potential of piperine in 7,12-dimethylbenz[a]anthracene- induced skin carcinogenesis in Swiss albino mice.", Environ Toxicol Pharmacol, Volume 28, Number 1, 2009, pp. 11-18. 2009.
Shanmugam Manoharan, Kuppusamy Panjamurthy, Subramanian Balakrishnan, Kalaiarasan Vasudevan and Lakshmanan Vellaichamy , "Circadian time dependent chemopreventive potential of Withaferin-A in 7,12-dimethylbenz(a)anthracene-induced oral carcinogenesis.", Pharmacol Rep, Volume 61, Number 1, 2009, pp. 509-516. 2009.
Sasikumar D, Manoharan S, Prema S and Mathi S , "Evaluation of the effects of Terminalia Arjuna Bark Extracts on the cell surface glycoconjugates abnormalities in DMBA-induced hamster buccal pouch carcinogenesis..", Jamahiriya Medical Journal , Volume 9, Number 1, 2009, pp. 25-30. 2009.
Sebastian S, Sundaraganesan N and Manoharan S, "Molecular structure, spectroscopic studies and first-order molecular hyperpolarizabilities of Ferulic acid by Density functional study.", Spectrochim Acta A Mol Biomol Spectrosc., Volume 74, Number 2, 2009, pp. 312-323. 2009.
Karpagam J, Sundaraganesan N, Sebastian S, Manoharan S and Kurt M , "Molecular structure, vibrational spectroscopic, first-order hyperpolarizability and HOMO, LUMO studies of 3-hydroxy-2-naphthoic acid hydrazide.", J Raman Spectroscop., Volume 41, Number 1, 2009, pp. 53-62. 2009.
Krishnakumar N, Manoharan S, Palaniappan PR, Venkatachalam P, Manohar MG. , "Chemopreventive efficacy of piperine in 7,12-dimethyl benz [a] anthracene (DMBA)-induced hamster buccal pouch carcinogenesis: An FT-IR study. .", Food Chem Toxicol, Volume 47, Number 14, 2009, pp. 2813-2820. 2009.
Manoharan S, Singh RB, Balakrishnan S , "Chemopreventive mechanism phytochemicals in oral, mammary and skin carcinogenesis: an overview.", Open Nutraceutical Journal, Volume 2, Number 1, 2009, pp. 52-63. 2009.
S. Manoharan, R. Anish Kumar, A. Linsa Mary, R.B. Singh, S. Balakrishnan and S. Silvan , "Effects of Punica granatum Flowers on Carbohydrate Metabolizing Enzymes, Lipid Peroxidation and Antioxidants Status in Streptozotocin Induced Diabetic Rats.", Open Neutraceutical Journal, Volume 2, Number 1, 2009, pp. 113-117. 2009.
Balakrishnan S, Menon VP, Manoharan S and Rajalingam K, "Antigenotoxic effect of ferulic acid in 7,12-dimethylbenz(a)anthracene (DMBA) induced genotoxicity.", Afr. J. Trad. CAM, Volume 5, Number 1, 2008, pp. 32-38. 2008.
Rajalingam K, Renju G.L, Balakrishnan S and Manoharan S. , "Effect of Clerodendron inerme on erythrocyte membrane integrity during 7,12-dimethylbenz(a)anthracene induced skin carcinogenesis in Swiss albino mice.", J Sci Res, Volume 1, Number 3, 2008, pp. 246-255. 2008.
Panjamurthy K, Manoharan S. Menon VP and Madhavan RN , "Withaferin-A protects 7, 12 – dimethylbenz(a)anthracene induced genotoxicity in bone marrow of Syrian golden hamsters.", J Biochem Mol Toxicol, Volume 22, Number 2, 2008, pp. 251-258. 2008.
Balakrishnan S, Menon VP, and Manoharan S , "Chemopreventive Efficacy of Ferulic acid in 7,12-dimethylbenz(a)anthracene Induced Hamster Buccal Pouch Carcinogenesis.", J Med Food, Volume 11, Number 4, 2008, pp. 693-700. 2008.
Shanmugam Manoharan, Kannan Kavitha, Subramanian Balakrishnan and Kasinathan Rajalingam, "Clerodendron inerme protects cellular integrity during 7,12-dimethylbenz[a]-anthracene-induced hamster buccal pouch carcinogenesis.", Afr. J. Trad. CAM, Volume 5, Number 2, 2008, pp. 213-222. 2008.
Subramanian Balakrishnan, Lakshmanan Vellaichamy, Venugopal P. Menon and Shanmugam Manoharan , "Antigenotoxic effects of curcumin and piperine alone or in combination against 7,12–dimethylbenz(a)anthracene induced genotoxicity in bone marrow of golden Syrian hamsters.", Toxicol Mech Methods, Volume 18, Number 9, 2008, pp. 691-696. 2008.
Vasudevan, K., Manoharan, s., Panjamurthy, K., Lellaichamy, L. and Chellammal, A , "Evaluation of antihyperglycemic effect of Cassia fistula (linn.) leaves in streptozotocin induced diabetic rats.", E J Pharmacol Ther, Volume 1, Number 1, 2008, pp. 57-60. 2008.
Balakrishnan S, Manoharan S, Linsa Mary A, Panjamurthy K, Vellaichamy L, Vasudevan K, "Circadian time dependent chemopreventive efficacy of curcumin and ferulic acid in 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis..", E J Pharmacol Ther, Volume 1, Number 1, 2008, pp. 61-66. 2008.
K. Vasudevan, S. Manoharan, Linsa mary alias, S. Balakrishnan, L. Vellaichamy and M. Gitanjali. , "Evaluation of chemopreventive efficacy of Cassia fistula in 7, 12–dimethyl benz(a) anthracene (DMBA) induced oral carcinogenesis..", Int. J. Chem. Sci. , Volume 6, Number 3, 2008, pp. 1341-1354. 2008.
Pavana P, Sethupathy S, Manoharan S , "Protective role of Tephrosia purpurea ethanolic seed extract on glycoprotein components in streptozotocin induced diabetic rats.", Int J Pharmacol, Volume 4, Number 1, 2008, pp. 114-119. 2008.
Pavana P, Manoharan S, Renju G L, and Sethupathy S. , "Antihyperglycemic and antihyperlipidemic effects of tephrosia purpurea leaf extract in streptozotocin induced diabetic rats.", J Environ Biol, Volume 28, Number 4, 2007, pp. 833-837. 2007.
Sophia D and Manoharan S, "Hypolipidemic effects of Ficus racemosa (Linn.) in alloxan induced diabetic rats..", Afr.J.Trad.CAM, Volume 4, Number 3, 2007, pp. 279-288. 2007.
Pavana P, Sethupathy S and Manoharan S , "Antihyperglycemic and antilipidperoxidative effects of tephrosia purpurea leaf extracts in streptozotocin induced diabetic rats..", J Nat Remi, Volume 7, Number 1, 2007, pp. 43-49. 2007.
Suresh K, Manoharan S, Panjamurthy K and Senthil N , "Modifying effects of Annona squamosa on glycoconjugates levels in 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.", J Med Sci, Volume 7, Number 1, 2007, pp. 100-105. 2007.
Vasudevan K, Sophia D, Balakrishnan S and Manoharan S , "Antihyperglycemic and antilipidperoxidative effects of Ficus racemosa (Linn.) bark extracts in alloxan induced diabetic rats.", J Med Scie, Volume 7, Number 3, 2007, pp. 330-338. 2007.
Renju G L, Manoharan S, Balakrishnan S and Senthil N , "Chemopreventive and antilipidperoxidative potential of Clerodendron inerme (L) Gaertn in 7,12-dimethylbenz(a)anthracene (DMBA) indcued skin carcinogenesis in Swiss albino mice.", Pak J Biol Sci, Volume 10, Number 9, 2007, pp. 1465-1470. 2007.
Senthil N, Manoharan S, Balakrishnan S, Ramachandran C R and Muralinaidu R , "Chemopreventive and antilipidperoxidative efficacy of Piper longum (Linn.) on 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis.", J App Sciences, Volume 7, Number 7, 2007, pp. 1036-1042. 2007.
Senthil N, Manoharan S, Balakrishnan S, Ramachandran CR, Muralinaidu R and Rajalingam K, "Modifying effects of Piper longum on cell surface abnormalities in 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.", Intl J Pharmacol, Volume 3, Number 3, 2007, pp. 290-294. 2007.
Punitha R, Manoharan S , "Antihyperglycemic and antilipidperoxidative effects of Pongamia pinnata (Linn.) Pierre flowers in alloxan induced diabetic rats.", J Ethnopharmacol, Volume 105, Number 1-2, 2006, pp. 39-46. 2006.
Kavitha K, Manoharan S, and Suresh K. , "Temporal patterns of blood lipidperoxides and antioxidants in 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis.", Int J Pharmcol, Volume 2, Number 4, 2006, pp. 394-399. 2006.
Manoharan S, Kavitha K, Senthil N, Renju G L. , "Evaluation of anticarcinogenic effects of Clerodendron inerme (L.) Gaertn on 7, 12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis. .", Singapore Med J, Volume 47, Number 12, 2006, pp. 1038-1043. 2006.
Suresh K, Manoharan S, Panjamurthy K and Kavitha K , "Chemopreventive and antilipidperoxidative efficacy of Annona squamosa bark extracts in experimental oral carcinogenesis.", Pak J Biol Sci, Volume 9, Number 14, 2006, pp. 2600-2605. 2006.
Panjamurthy K, Manoharan S, Sambath Kumar G and Suresh K, "Evaluation of anti-inflammatory and anti-lipidperoxidative effects of Tephrosia purpurea (Linn.) Pers on carrageenan induced rat paw oedema.", J Med Sciences, Volume 9, Number 1-2, 2006, pp. 54-59. 2006.
Panjamurthy K, Manoharan S, Ramachandran CR, "Lipid peroxidation and antioxidant status in patients with periodontitis.", Cell Mol Biol Lett, Volume 10, Number 1-2, 2005, pp. 255-264. 2005.
Manoharan S, Baskar AA, Manivasagam T, Subramanian P, "Circadian rhythmicity of plasma lipid peroxidation and antioxidants in oral squamous cell carcinoma.", Singapore Med J, Volume 46, Number 4, 2005, pp. 184-188. 2005.
Kolanjiappan K, Manoharan S, "Chemopreventive efficacy and anti-lipid peroxidative potential of Jasminum grandiflorum Linn. on 7,12-dimethylbenz(a)anthracene induced rat mammary carcinogenesis.", Fund Clin Pharmacol, Volume 19, Number 1, 2005, pp. 687-693. 2005.
Kolanjiappan K, Manoharan S. , "Diurnal rhythmicity of thiobarbituric acid reactive substances and antioxidants in experimental mammary carcinogenesis.", Exp. Oncol, Volume 27, Number 4, 2005, pp. 298-302. 2005.
Dakshayani KB, Subramanian P, Manivasagam T, Mohammad Essa M, Manoharan S, "Melatonin modulates the oxidant and antioxidant imbalance during n-nitrosodiethylamine induced hepatocarcinogenesis in rats.", J Pharm Pharmaceut Sci, Volume 8, Number 2, 2005, pp. 316-321. 2005.
Manoharan S, Padmanabhan M, Kolanjiappan K, Ramachandran CR, Suresh K. , "Analysis of glycol-conjugates in patients with oral squamous cell carcinoma.", Clinica Chimica Acta, Volume 339, Number 1-2, 2004, pp. 91-96. 2004.
Albert Baskar A, Manivasagam T, Manoharan S, Subramanian P. , "Temporal patterns of lipid peroxidation products and antioxidants in oral cancer patients.", Cellular & Molecular Biology Letters, Volume 9, Number 1-2, 2004, pp. 665-673. 2004.
D. Vijayakumar, K. Suresh, S. Manoharan., "Lipid peroxidation and antioxidant status in blood of rheumatoid arthritis patients.", J Med Sci, Volume 7, Number 2, 2004, pp. 104-108. 2004.
Vijayamalini M, Manoharan S., "Lipid peroxidation, Vitamin C, E and reduced glutathione levels in patients with pulmonary tuberculosis.", Cell Biochemistry and Function, Volume 22, Number 1, 2004, pp. 19-22. 2004.
Manoharan S, Kolanjiappan K, Ramachandran CR, Sethupathy S, Kayalvizhi M, "Enhanced lipid peroxidation and impaired enzymic antioxidants activities in erythrocytes of patients with cervical carcinoma.", Cellular & Molecular Biology Letters, Volume 9, Number 1-2, 2004, pp. 699-707. 2004.
Senthil N and Manoharan S, "Lipid peroxidation and antioxidants status in patients with papillary thyroid carcinoma.", AJPCN, Volume 13, Number 1, 2004, pp. 391-395. 2004.
Kolanjiappan, K., Ramachandran, C.R. and Manoharan, S. , "Biochemical changes in tumor tissues of oral cancer patients.", Clin. Biochem, Volume 36, Number 1, 2003, pp. 61-65. 2003.
Manoharan S, Kolanjiappan K, Sethupathy S and Kayalvizhi M. , "Lipid peroxidation and antioxidant status in cervical cancer patients.", JBMBB, Volume 6, Number 3, 2002, pp. 225-227. 2002.
Kolanjiappan, K., Manoharan, S. and Kayalvizhi, M. , "Measurement of erythrocyte lipids, lipid peroxidation, antioxidants and osmotic fragility in cervical cancer patients.", Clin. Chim. Acta, Volume 326, Number 1, 2002, pp. 143-149. 2002.
Nagini, S., Manoharan, S. and Ramachandran, C.R. , "Lipid peroxidation and antioxidants in oral squamous cell carcinoma.", Clin. Chim. Acta, Volume 273, Number 1, 1998, pp. 95-98. 1998.
Nagini, S. and Manoharan, S., "Biomonitoring the Chemopreventive potential of the plant products neem and turmeric in 4NQO induced oral carcinogenesis.", J. Clin. Biochem. Nutr, Volume 23, Number 2, 1997, pp. 33-40. 1997.
Manoharan, S., Shreeram, S. Nagini, S, "Lifestyle can induce lipid peroxidation and compromise of antioxidant defence mechanisms in erythrocytes of oral cancer patients.", Med. Sci. Res. , Volume 24, Number 1, 1996, pp. 397-400. 1996.
Manoharan, S., RamachandranC.R., RamachandranV. and Nagini, S., "Inhibition of 4NQO induced oral carcinogenesis by plant products.", J. Clin. Biochem. Nutr, Volume 21, Number 2, 1996, pp. 141-149. 1996.
Manoharan, S. and Nagini, S. , "Risk factors alter glycoprotein levels in oral cancer patients.", Med. Sci. Res. , Volume 23, Number 1, 1995, pp. 229-230. 1995.
Manoharan, S. and Nagini, S. , "Oral cancer – A Review Trends.", Life Sci, Volume 10, Number 2, 1995, pp. 83-90. 1995.
Manoharan, S., Ramachandran,C.R., Nagini, S, "Altered lipid profile in oral cancer patients is due to life style.", Med. Sci. Res. , Volume 23, Number 1, 1995, pp. 493-495. 1995.
Manoharan, S. and Nagini, S. , "Lipid peroxidation and antioxidant status in oral cancer patients.", Med. Sci. Res. , Volume 22, Number 1, 1994, pp. 291-292. 1994.
List of Conferences - National
Balakrishnan S, Manoharan¬¬ S, Effect of ferulic acid on cell surface and circulatory glycoconjugates and lipids status in 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis., CSIR-ICMR-TNSCST sponsored National conference on Diabetes mellitus and Cancer, Dec 19-20, 2009, ANNAMALAI UNIVERSITY, pp. 116-121. New Delhi, Excel India publishers.
Vinothkumar V, Manoharan S , Geraniol – a potent antigenotoxic agent., CSIR-ICMR-TNSCST sponsored National conference on Diabetes mellitus and Cancer, Dec 19-20, 2009, ANNAMALAI UNIVERSITY, pp. 139-143. New Delhi, Excel India publishers.
Suresh K, Sugunadevi G, Vijaianand MA, Manoharan S , Chemopreventive and antioxidant efficacy of Mosinone-A in experimental oral carcinogenesis, CSIR-ICMR-TNSCST sponsored National conference on Diabetes mellitus and Cancer, Dec 19-20, 2009, ANNAMALAI UNIVERSITY, pp. 144-149. New Delhi, Excel India publishers.
Senthil N, Silvan S, Balakrishnan S, Manoharan S , Antigenotoxic effect of Piper longum dried fruits extract in DMBA-induced genotoxicity, CSIR-ICMR-TNSCST sponsored National conference on Diabetes mellitus and Cancer, Dec 19-20, 2009, ANNAMALAI UNIVERSITY, pp. 171-175. New Delhi, Excel India publishers.
Manoharan S, Balakrishnan S, Vellaichamy L, Linsa Mary A & Angel R. Reena. , Protective effects of curcumin and piperine on cellular integrity during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis, New Innovation in Cancer Research and Experimental Therapeutics, Jan 5-6, 2009, coimbatore, pp. 4-11. New Delhi, Excel India publishers.
Panjamurthy K, Manoharan S, Pugalendhi P, Suresh K, Kumar RA & Baskarn N , Modulating effect of Withaferin-A on circadian pattern of circulatory lipid peroxidation and antioxidants during 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis, New Innovation in Cancer Research and Experimental Therapeutics, Jan 5-6, 2009, coimbatore, pp. 50-55. New Delhi, Excel India publishers.
List of Book Published
Manoharan S , Research and review articles presented in CSIR-ICMR-TNSCST sponsored National conference on Diabetes mellitus and Cancer., New Delhi: Excel India publishers, 978-93-80043-56-2, pp. Dec 2009.
Manoharan, S. , Oral Cancer: An avoidable and preventable cancer, Chidambaram: RASI , 978–93–5087-438–7, pp. Dec 2012.
Shanmugam Manoharan, Food, Nutrition and Eating Behavior. Chapter 10 - “Low W-6/W-3 ratio dietary pattern and risk of cardiovascular disease and diabetes mellitus”, New York: Nova Science Publishers, 978-1-62948-234-7, pp. 105-138. Feb 2014.
List of Awards /Honours / Memberships
International college of nutrition - -
LifeMember -Indian Society of Chronobiology - -
LifeMember - Society of Biological Chemists (ANNAMALAINAGAR) - 2015