Bio-medical research is important in the development of many major medical advances that helps the researchers to perform life-changing discoverie slike new vaccines,drugs, drug delivery systems, prostheses, anesthetics, blood transfusions etc. Preclinical trials in bio medical research is conducted in experimental animals like Rats, Mice, Guinea pigs, Hamsters and Rabbits for bio-medical research, safety assessment of certain consumer products and chemical substances.
Central Animal House, the centralized experimental animal facility of Annamalai University located in an area of 1674 Sq.M with buildings occupying 494.53 Sq.M inside the premises of Rajah Muthiah Medical College since 1988 and is playing a key role for the bio-medical research of staff and students of Annamalai University. Many high impact scientific publications of Annamalai University are based on the animal experimental studies conducted in this facility.
This facility was the handcrafted efforts of Dr.P.S.R.K.Haranath, Professor & Head, Department of Pharmacology, Rajah Muthiah Medical College, Annamalai University from February 1988 to January 1992. Followed by him , Dr.S.Vembar , Professor & Head, Department of Pharmacology was in charge of the Central Animal House ( February 1992 to June 1999) , Dr.P.Muralidhar between September 1999 and June 2006 , Dr.P.Nirmala between July 2006 and March 16th, 2016. Presently, the Central Animal House is headed by Dr.S.Vigil Anbiah, Associate Professor & Head i/c.
UNIQUENESS OF THE FACILITY
KEY RESEARCH AREAS
- 1. The Central Animal House is a centralized facility for bio-medical research by the staff and research scholars of Pharmacology, Pharmacy, Medicine, Dentistry, Biochemistry & Biotechnology, Marine Biology , Zoology and Agriculture.
- 2. As per the approval granted by the Institutional Animal Ethics Committee the animal experimental studies will be carried out in this facility. Basic facilities for rearing the animals are provided in-house.
- 3. The Central Animal House is a mandatory requirement for the affiliations of Medical Council of India (MCI) , Pharmacy Council of India (PCI) and Indian Council of Agricultural Research ( ICAR)
- 4. The experimental animals are bred in the breeding unit and the experiments are conducted in the experimental unit of the Central Animal House.
- 5. After the completion of experiments, the carcass will be disposed as per the norms of Tamil Nadu Waste Management Ltd.
- 6. Suitable animal handling trainings are given by veterinarians to the research scholars before commencing the experiments.
Animal experiments are conducted in the following key research areas which helped the researchers to publish their findings in reputed scientific journals.
- 1. Diabetes studies
- 2. Cancer studies
- 3. Studies on hepato toxicity.
- 4. Hypersensitivity studies
- 5. Dermatological studies
- 6. Oral maxillo facial studies
- 7. Neurological studies
- 8. Animal behavioral studies
- 9. Cardio protective studies
- 10. Urolith studies
- 11. Fertility studies
- 12. Anti inflammatory and anti oxidant studies.
- 13. Studies on analgesics
- 14. Metabolic studies
- 15. Studies on stress tolerance
- 16. Wound healing studies
- 17. Drug bio availability studies.
- 18. Studies on drug delivery system.
- 19. Pharmacological evaluation studies.
- 20. Studies on various phyto-chemicals.
- 21. Chemical toxicity studies.
- 22. Studies on marine bio products.
- 23. Studies on marine fish toxin
- 24. Pollution studies.
- 25. Studies on sea weeds.
The Central Animal House is functioning under the direct supervision of Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), Ministry of Fisheries , Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying , Government of India.
The facility is presently functioning with a registration number 160 / PO / ReBi / S / 1999 / CPCSEAfor Research for Education purpose and Breeding in house use of small animals.The registration isrenewed on 3.5.2020 for a period of five years (renewal order enclosed).
Central Animal House comes under the purview of Institutional Animal Ethics Committee (IAEC) which is formed by CPCSEA, Govt. of India for approval and supervision of experiments on laboratory animals such as Rats, Mice , Guinea Pigs, hamsters and Rabbits for research scholars and staff members of Annamalai University.
ANIMAL HEALTH MONITORING
A team of three veterinarians and three supporting staff of Central Animal House take care of the breeding of animals, general health monitoring, supervision and monitoring of animal experiments as per CPCSEA guidelines. The veterinarians are trained by appropriate competing agencies like CPCSEA and FELASA (Federation of European Laboratory Animal Sciences Association).
Training programmes are conducted in the Central Animal house so as to train the research scholars in the handling of experimental animals.
FACILITIES OF CENTRAL ANIMAL HOUSE
- 1. Breeding of experimental animals
- 2. Experimental facility for the staff and research scholars.
- 3. Separate quarantine facility.
- 4. Poly carbonate animal cages.
- 5. Animal restraining devices
- 6. Animal health monitoring devices.
- 7. Horizontal rectangular type autoclave for sterilization purpose.
- 8. Biological waste disposal facility.
| ||Dr. S. VIGIL ANBIAH||ASSOCIATE PROFESSOR & HEAD i/c|
(CENTRAL ANIMAL HOUSE - RMMC)