Annamalai University
Faculty Member Details

Staff Id : 13637
Name : Dr. G. SINDHU (Deputed)
Qualification : M.Sc.,M.Phil.,Ph.D.,
Specialization : Cancer biology and Nephroprotection studies
Date of Birth : 05-05-1978
Date of Joining : 11-07-2007
Present Address Contact Number E-Mail Address
No.3,1 st cross,Varalakshmi garden,
Chidambaram- 608 104
Research Guidance
Discipline Awarded Guidance
M.Phil./M.E./M.Sc. 2-
Ph.D. 33

Conference /Seminar / Symposia / Workshop
Conference Seminar Symposia Workshop
National International
Attended 2512213
Conducted 422-3

Research Projects
Major Projects Minor Projects Total Amount (Rs.)
Completed 1-12,57,833
Ongoing -11,00,000
Teaching and Research Experience Industry Experience
16 Years -
Journals Conference Books Published Popular Article
National International National International
- 23 3 1 1 -

List of Publications - International
Lakshmanan Vennila and Ganapathy Sindhu, "Risk factors of cardiovascular diseases: A review.", AJANTA, Volume 8, Number 2, Apr 2019, pp. 119-123. 2019.
Ganapathy Sindhu and Lakshmanan Vennila, "The future of integrative health and medicine in India.", AJANTA, Volume 8, Number 2, Apr 2019, pp. 119-123. 2019.
Gopalakrishnan Thamizharasi, Ganapathy Sindhu, Veeran Veeravarmal, Namasivayam Nalini, "Preventive effect of D-carvone during DMBA induced mouse skin tumorigenesis by modulating xenobiotic metabolism and induction of apoptotic events.", Biomedicine & Pharmacotherapy, Volume 111, Number 3, Mar 2019, pp. 178-187. 2019.
Gopalakrishnan Thamizharasi, Ganapathy Sindhu, "D-carvone inhibits growth, migration, cell cycle at G0 /G1 phase and induces apoptosis in A431 cells by disrupting mitochondrial membrane potential.", Int.J.Res.Pharm.Sci, Volume 9, Number 4, Sep 2018, pp. 1465-1475. 2018.
Vijayalakshmi A, Sindhu G, "Data on efficacy of umbelliferone on glycoconjugates and immunological marker in 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis.", Data Brief., Volume 21, Number 15, Sep 2017, pp. 216-221. 2017.
Vijayalakshmi A, Sindhu G, "Umbelliferone arrest cell cycle at G0/G1 phase and induces apoptosis in human oral carcinoma (KB) cells possibly via oxidative DNA damage.", Biomed Pharmacother, Volume 92, Number 1, Aug 2017, pp. 661-671. 2017.
Annamalai Vijayalakshmi, Ganapathy Sindhu, "Dose responsive efficacy of umbelliferone on lipid peroxidation, anti-oxidant, and xenobiotic metabolism in DMBA-induced oral carcinogenesis.", Biomedicine & Pharmacotherapy, Volume 88, Number 1, Apr 2017, pp. 852-862. 10.1016/j.biopha.2017.01.064.
Sharmila R, Sindhu G, "Evaluate the Antigenotoxicity and Anticancer Role of β-Sitosterol by Determining Oxidative DNA Damage and the Expression of Phosphorylated Mitogen-activated Protein Kinases', C-fos, C-jun, and Endothelial Growth Factor Receptor..", Pharmacogn Mag, Volume 13, Number 49, Jan 2017, pp. 95-101. 10.4103/0973-1296.197634.
Sharmila, R. and Sindhu, G. , "Modulation of Angiogenesis, Proliferative Response and Apoptosis by β-Sitosterol in Rat Model of Renal Carcinogenesis..", Ind J Clin Biochem, Volume 32, Number 2, May 2016, pp. 142-152. 10.1007/s12291-016-0583-8.
Sharmila, R. and Sindhu, G, "Downregulation of TNF-α, NF-κB p65, COX-2 and iNOS by β-Sitosterol ameliorate the toxic effect of Fe-NTA on renal tissue..", Int J Pharm Bio Sci, Volume 7, Number 3, Jul 2016, pp. 760-766. 2016.
Ramalingam Sharmila, Ganapathy Sindhu and Pushpam Marie Arockianathan, "Nephroprotective effect of β-sitosterol on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute nephrotoxicity in Wistar rats..", J Basic Clin Physiol Pharmacol, Volume 27, Number 5, Sep 2016, pp. 473-482. 2016/10.1515/jbcpp-2015-0085.
Ramalingam Sharmila and Ganapathy Sindhu. , "Bioavailability study of β-sitosterol in rat plasma after oral administration: evaluation using HPLC..", IJSAR, Volume 2, Number 7, 2015, pp. 55-60. 2015.
Sindhu G, Nishanthi E, Sharmila R, "Nephroprotective effect of vanillic acid against cisplatin induced nephrotoxicity in wistar rats: a biochemical and molecular study..", Environ Toxicol Pharmacol, Volume 39, Number 1, Jan 2015, pp. 392-404. 10.1016/j.etap.2014.12.008.
A.Vijayalakshmi , R.Sharmila, N.K.S.Gowda and G.Sindhu, "Study on antifungal effect of herbal compounds against mycotoxin producing fungi.", Journal of Agricultural Technology, Volume 10, Number 6, Nov 2014, pp. 1587-1597. 2014.
Ganapathy Sindhu, Ramalingam Sharmila, Emayavaramban Nishanthi, Annamalai Vijayalakshmi, Gopalakrishnan Tamizharasi, "Trianthema decandra (L.): A nephroprotector during gentamicin-induced nephrotoxicity in male wistar rats.", European Journal of Molecular Biology and Biochemistry, Volume 1, Number 5, Sep 2014, pp. 169-175. 2014.
Sindhu G, Susithra M and Vijayalakshmi, "Evaluation of hepatoprotective effect of berberine in paracetamol induced experimental hepatotoxicity in wistar rats.", International Journal of Recent Scientific Research, Volume 3, Number 7, Jul 2012, pp. 569-573. 2012.
Shanmugam Manoharan, Raju Kowsalya, Nagarethinam Baskaran, Simon Silvan, Ganapathy Sindhu, Veerasamy Vinothkumar, "Protective effect of 18β-glycyrrhetinic acid on cell surface glycoconjugates abnormalities in 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis.", International Journal of nutrition, pharmacology, neurological diseases, Volume 2, Number 2, May 2012, pp. 151-155. 2012.
Vinothkumar V, Manoharan S, Sindhu G, Nirmal MR, Vetrichelvi V, "Geraniol modulates cell proliferation, apoptosis, inflammation, and angiogenesis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.", Mol Cell Biochem, Volume 369, Number 1-2, Oct 2012, pp. 17-25. 2012.
Manoharan S, Sindhu G, Vinothkumar V, Kowsalya R, "Berberine prevents 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis: A biochemical approach.", Eur J Can Prev , Volume 21, Number 2, Mar 2012, pp. 182-192. 2012.
Shanmugam Manoharan, Ganapathy Sindhu, Madhavan Ramados Nirmal, Venkatesan Vetrichelvi and Subramanian Balakrishnan, "Protective effect of berberine on expression pattern of apoptotic, cell proliferative, inflammatory and angiogenic markers during 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis..", Pakistan Journal of Biological Sciences , Volume 14, Number 20, 2011, pp. 918-932. 2011.
Sindhu G, Manoharan S, "Berberine protects cellular integrity during 7,12-dimethylbenz[a]anthracene- induced oral carcinogenesis in golden Syrian hamsters.", Journal of Cell and Tissue Research , Volume 10, Number 2, Jun 2010, pp. 2185-2190. 2010.
Sindhu G, Manoharan S, "Anti-clastogenic effect of berberine against DMBA-induced clastogenesis.", Basic ClinPharmacol Toxicol , Volume 107, Number 4, Oct 2010, pp. 818-824. 2010.
Sindhu G, Prabhu N and Kamalakumar C, "Antibacterial activities of flavonoids obtained from the root extract of Trianthemadecandra L.", Asian. J. Microbiol. Biotech. Env.Sc, Volume 11, Number 1, 2009, pp. 133-135. 2009.
List of Conferences - National
Sindhu G, Manoharan S, Effect of berberine on cellular integrity during 7,12-dimethylbenz[a]anthracene-induced oral carcinogenesis, MCAS-BIO-2010 "Biotechnology:Great Expectation and Achievements", Jan 8-9, 2010, Rasipuram, pp. 123-123. Rasipuram, Centre for Biotechnology, Muthayammal College of arts and science.
G.Sindhu and S.Manoharan, Protective effect of berberine on MnPCEs frequency and chromosomal aberrations in 7,12-dimethylbenz(a)anthracene induced genotoxicity, Dia-Can'08, Dec 20-21, 2008, Annamalai University, Chidambaram , pp. 24-24. Annamalainagar, Department Biochemistry and Biotechnology.
G.Sindhu, Trianthema decandra Linn root extract protects against gentamicin-induced nephrotoxicity in male wistar rats, Natural products in Health and Disease, Feb 29-2, 2008, Annamalai University, Chidambaram , pp. 15-15. Annamalainagar, Department Biochemistry and Biotechnology.
List of Conferences - International
G.Sindhu and S.Manoharan, Antiproliferative and apoptosis inducing effect of berberine in 7,12-dimethylbenz[a]anthracene inducedhamster buccal pouch carcinogenesis, ISARCON, Sep 1-3, 2012, Annamalai University, Chidambaram , pp. 89-90. Annamalainagar, Department Biochemistry and Biotechnology.
List of Book Published
Manoharan S, Silvan S, Sindhu G and Manoj Prabhakar, Chapter-IV: Signs, symptems, diagnosis and staging of oral cancer. Oral Cancer: An Avoidable and preventable Cancer.2012; 45-59. ISBN: 978-93-5087-438-7., Chidambaram: Rasi, 978-93-5087-438-7., pp. 45-59. Dec 2012.
List of Awards /Honours / Memberships
International College of Nutrition - --
Life member - Society of Biological Chemists (Annamalainagar) - 2024